Optimal Design for Nonlinear Response Models
||Fedorov, Valerii V.|
Leonov, Sergei L.
|Series title:||Chapman and Hall/CRC Biostatistics Ser.|
|Publication Date:||Jul 2013|
| Publisher:||CRC Press LLC|
| Book Format:||Hardback|
|List Price:||USD $89.95|
| Book Description: |
Optimal Design for Nonlinear Response Modelsdiscusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors' many years of experience in academia and the pharmaceutical industry.
While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models...