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Resistance to Proteasome Inhibitors in Cancer

Molecular Mechanisms and Strategies to Overcome Resistance

Resistance to Proteasome Inhibitors in Cancer( )
Editor: Dou, Q. Ping
Series title:Resistance to Targeted Anti-Cancer Therapeutics Ser.
ISBN:978-3-319-06751-3
Publication Date:Sep 2014
Publisher:Springer
Book Format:Hardback
List Price:USD $199.99
Book Description:

The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, histone deacetylases, oxidative stress and proteotoxic stress pathways and pharmacogenomic signature profiling) in resistant cancer cells. The mechanisms of action and resistance of...
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Book Details
Pages:390
Detailed Subjects: Medical / Oncology
Physical Dimensions (W X L X H):6.045 x 9.165 Inches
Book Weight:17.611 Pounds



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