ABC Transporters in Human Disease |
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| Author:
| Moitra, Karobi |
| Series title: | Colloquium Series on the Genetic Basis of Human Disease Ser. |
| ISBN: | 978-1-61504-378-1 |
| Publication Date: | Apr 2012 |
| Publisher: | Morgan & Claypool Life Science Publishers
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| Book Format: | Paperback |
| List Price: | AUD $57.00 |
Book Description:
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The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates so far studied. The human ABC transporter superfamily contains 48 genes, subdivided into 7 subfamilies ranging from A to G. The ABC proteins encoded by these genes are ATP-driven transmembrane pumps, some of which possess the capacity to efflux harmful toxic substances and therefore play a key role in xenobiotic defense.
The ATP-binding cassette (ABC) transporter genes are ubiquitous in the genomes of all vertebrates so far studied. The human ABC transporter superfamily contains 48 genes, subdivided into 7 subfamilies ranging from A to G. The ABC proteins encoded by these genes are ATP-driven transmembrane pumps, some of which possess the capacity to efflux harmful toxic substances and therefore play a key role in xenobiotic defense.