Antibase 2013 Upgrade - the Natural Compound Identifier |
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| Author:
| Laatsch, |
| ISBN: | 978-3-527-33673-9 |
| Publication Date: | Jul 2013 |
| Publisher: | Wiley-VCH Verlag GmbH
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| Book Format: | Digital |
| List Price: | Contact Supplier contact
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Book Description:
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Progress in natural products chemistry today is progress in synthetic chemistry tomorrow. Structure determination of complex natural products delivers not only the most interesting, the most challenging targets for synthetic chemists, but is also the basis of new medical applications of the future. There is no doubt that natural product's isolation and structure identification is still one of the most important areas in chemistry.
An army of scientists tries to discover with...
More Description
Progress in natural products chemistry today is progress in synthetic chemistry tomorrow. Structure determination of complex natural products delivers not only the most interesting, the most challenging targets for synthetic chemists, but is also the basis of new medical applications of the future. There is no doubt that natural product's isolation and structure identification is still one of the most important areas in chemistry.
An army of scientists tries to discover with unlimited effort a limited number of natural metabolites: More than 170.000 natural products are known today, and every year are added about 700 new structures just only from micro-organisms. This gives rise to a major problem in natural product chemistry: it is unavoidable that certain common compounds are re-isolated again and again, a handicap which costs time and money, and is a steady source of avoidable frustration.
Antibase 2013, the Natural Compound Identifier, is a comprehensive database of more than 41,864 natural compounds, with close to 6% new entries from 2012 edition. The data in Antibase have been collected from the primary and secondary literature and then carefully checked and validated. AntiBase includes descriptive data (molecular formula and mass, elemental composition, CAS registry number); physico-chemical data (melting point, optical rotation); spectroscopic data (UV, 13C-NMR, IR and mass spectra); biological data (pharmacological activity, toxicity); information on origin and isolation and a summary of literature sources.
A unique feature of Antibase is the use of predicted 13C-NMR spectra for those compounds where no measured spectra are available. These spectra have been produced using the SpecInfo spectrum prediction algorithm.
Calculated high resolution molecular masses are included in the new update.
AntiBase is available in ChemFinder (Cambridgesoft) and Scidex formats.