Dipeptidyl Peptidase IV in Metabolism and the Immune Response |
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| Editor:
| Fleischer, Bernhard |
| Series title: | Molecular Biology Intelligence Unit Ser. |
| ISBN: | 978-3-540-60199-9 |
| Publication Date: | Jan 1995 |
| Publisher: | Springer
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| Book Format: | Hardback |
| List Price: | AUD $197.95 |
Book Description:
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In this book, leading experts in their field describe the enzymology and molecular biology of dipeptidyl peptidase IV/CD26 and its functions in metabolism and immune responses. CD26 is identical to the proteolytic enzyme dipeptidyl peptidase IV expressed in a variety of different tissues including epithelia and lymphocytes. CD26 binds and transports adenosine desaminase selectively in different tissues. It is also involved in T cell activation, providing stimulatory and co-stimulatory...
More DescriptionIn this book, leading experts in their field describe the enzymology and molecular biology of dipeptidyl peptidase IV/CD26 and its functions in metabolism and immune responses. CD26 is identical to the proteolytic enzyme dipeptidyl peptidase IV expressed in a variety of different tissues including epithelia and lymphocytes. CD26 binds and transports adenosine desaminase selectively in different tissues. It is also involved in T cell activation, providing stimulatory and co-stimulatory signals. It is a receptor for collagen and may be a marker for malignancy. Recent progress from a number of laboratories has shown that CD26/dipeptidyl peptidase IV plays a pivotal role in the response of T lymphocytes and may be involved in the pathogenesis of AIDS.