Updated and revised, this fourth edition of a perennial bestseller provides current and comprehensive information on all aspects of drug design and discovery. It describes how medicinal chemists the specific strategies employed by medicinal chemists to advance promising molecules into clinical use for the alleviation of disease. The fourth edition includes new chapters on products of natural origin as leads in drug design, chemical biology, ADME-tox properties, bioinformatics and...
More DescriptionUpdated and revised, this fourth edition of a perennial bestseller provides current and comprehensive information on all aspects of drug design and discovery. It describes how medicinal chemists the specific strategies employed by medicinal chemists to advance promising molecules into clinical use for the alleviation of disease. The fourth edition includes new chapters on products of natural origin as leads in drug design, chemical biology, ADME-tox properties, bioinformatics and chemoinformatics in drug research, combinatorial chemistry, parallel synthesis, high-throughput screening, imaging in drug design, computer modeling techniques, gene technology, and target validation.