Drug-Induced Valvular Heart Disease |
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| Author:
| Droogmans, Steven
Kerkhove, Dirk
Cosyns, Bernard
Roosens, Bram
Van Camp, Guy |
| Series title: | Cardiology Research and Clinical Developments Ser. |
| ISBN: | 978-1-61668-978-0 |
| Publication Date: | Oct 2010 |
| Publisher: | Nova Science Publishers, Incorporated
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| Imprint: | Nova Biomedical Books |
| Book Format: | Paperback |
| List Price: | AUD $85.95 |
Book Description:
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The notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and...
More DescriptionThe notion that drugs can induce valvular heart disease (VHD) has occurred since the sixties and has received a lot of attention in recent years. Overstimulation of the serotonin 2B receptor (5-HT2B) leads to valvular fibroblast proliferation and thickening of the valvular leaflets with reduced mobility and regurgitation as a consequence. This book focuses on different aspects of this distinct kind of valvulopathy including pathophysiology of drug-induced VHD, histopathological and echocardiographic characteristics,drugs associated with VHD, the influence of cumulative drug dose and risk factors and others.