Intermolecular Cross-Talk in Tumor Metastasis |
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| Editor:
| Skouteris, George G.
Nicolson, Garth, L. |
| Series title: | NATO Science Ser. |
| ISBN: | 978-90-5199-456-8 |
| Publication Date: | Jan 1999 |
| Publisher: | IOS Press, Incorporated
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| Book Format: | Hardback |
| List Price: | AUD $217.95 |
Book Description:
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Metastasis of tumours is a sequence of events taking place after the appearance of a primary tumour. The potency of a tumour to metastasise greatly depends on the molecular interactions between tumour components (cellular differentiation and heterogeneity, surface antigenic determinants etc.) and the micro-environment. The complexity and diversity in the composition of tissue micro-environment is in great extent determining the metastatic behaviour or a primary tumour. Extracellular...
More DescriptionMetastasis of tumours is a sequence of events taking place after the appearance of a primary tumour. The potency of a tumour to metastasise greatly depends on the molecular interactions between tumour components (cellular differentiation and heterogeneity, surface antigenic determinants etc.) and the micro-environment. The complexity and diversity in the composition of tissue micro-environment is in great extent determining the metastatic behaviour or a primary tumour. Extracellular matrix composition, rearrangement of cytoskeleton, cell antigenicity , expression of metastasis-related novel genes, cell adhesion and novel therapeutical approaches such as blockage of angiogenesis, are the major topics discussed in detail in this volume.