Modulation of Cardiac Calcium Sensitivity A New Approach to Increasing the Strength of the Heart |
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| Editor:
| Lee, John A.
Allen, David G. |
| ISBN: | 978-0-19-262347-8 |
| Publication Date: | Mar 1993 |
| Publisher: | Oxford University Press
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| Book Format: | Hardback |
| List Price: | AUD $222.68AUD $283.00 |
Book Description:
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Calcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side-effects associated with that mechanism of action. These drugs offer an excitingalternative approach...
More DescriptionCalcium sensitizers are a new class of drug which increases the force of contraction of the heart by increasing the calcium sensitivity of contractile proteins. Their development represents the first major innovation in the treatment of heart failure for over 200 years. Unlike other drugs in this area, they do not increase the intracellular calcium concentration and do not have the side-effects associated with that mechanism of action. These drugs offer an excitingalternative approach to the treatment of heart failure, and this volume provides an authoritative overview of the physiology, biochemistry, and clincial issues involved. It will be of interest topharmacologists, research and clinical cardiologists, and physiologists.