Thrombin and Singlet Oxygen (1AO2*) Main Factors of Hemostasis |
|
Editor:
| Stief, Thomas |
ISBN: | 978-1-62808-466-5 |
Publication Date: | Sep 2013 |
Publisher: | Nova Science Publishers, Incorporated
|
Book Format: | Hardback |
List Price: | AUD $273.95 |
Book Description:
|
Neutrophil granulocytes (PMN) are our primary defence cells against bacteria, fungi, parasites, or micro-thrombi. Their main weapons and signals are the reactive oxygen species (ROS), H2O2 being mother ROS, radicalic OH and non-radicalic 1ΔO2* being the two daughter ROS. 1ΔO2* is the most important ROS because it is harmful against "non-self" and harmless against "self". 1ΔO2* is highly reactive against S-H, S-S, or C=C groups and releases photons (hν). The...
More DescriptionNeutrophil granulocytes (PMN) are our primary defence cells against bacteria, fungi, parasites, or micro-thrombi. Their main weapons and signals are the reactive oxygen species (ROS), H2O2 being mother ROS, radicalic OH and non-radicalic 1ΔO2* being the two daughter ROS. 1ΔO2* is the most important ROS because it is harmful against "non-self" and harmless against "self". 1ΔO2* is highly reactive against S-H, S-S, or C=C groups and releases photons (hν). The activation of the assembly of their NADPH-oxidase, one main trigger (zymosan A) and one main primer (1ΔO2*/hv) are of great physiological and pathophysiological importance in inflammation and in hemostasis. There is photonic communication: the neutrophils generate different types of photons and they can "see" them in other cells. The approximate 300-400 nm photons are the main signals and the photons of lowest wave length seem to especially alert them in emergency.