Advances in Medicinal Chemistry |
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| Editor:
| Maryanoff, B. E.
Maryanoff, C. A. |
| Series title: | Issn Ser. |
| ISBN: | 978-0-08-052636-2 |
| Publication Date: | Jan 1996 |
| Publisher: | Elsevier Science & Technology Books
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| Book Format: | Ebook |
| List Price: | USD $72.95USD $87.54 |
Book Description:
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Volume 3 of
Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents the medicinal chemistry...
More DescriptionVolume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents the medicinal chemistry and preclinical development surrounding sertraline, a very important serotonin reuptake drug for the treatment of endogenous depression. Finally, Chapter 4 gives a summary of a series of boronic acid-based immunosuppressants that operate via inhibition of dipeptidypeptidase IV.