Comprehensive Medicinal Chemistry II, Volume 5 Adme-Tox Approaches |
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| Editor:
| van de Waterbeemd, Han
Testa, Bernard |
| ISBN: | 978-0-08-044518-2 |
| Publication Date: | Nov 2006 |
| Publisher: | Elsevier Science & Technology
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| Book Format: | Hardback |
| List Price: | USD $575.00 |
Book Description:
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To be effective a drug must be Absorbed then Distributed to the site of action. It must also be Metabolised and Excreted without any measurable Toxicity (ADMET). This volume examines major ADMET issues, tools to measure these properties in vivo and in vitro and in-silico tools to predict and analyse effects. It concludes with a review of tools that can assist drug discovery in its early development stage.
To be effective a drug must be Absorbed then Distributed to the site of action. It must also be Metabolised and Excreted without any measurable Toxicity (ADMET). This volume examines major ADMET issues, tools to measure these properties in vivo and in vitro and in-silico tools to predict and analyse effects. It concludes with a review of tools that can assist drug discovery in its early development stage.