DNA Methylation Microarrays Experimental Design and Statistical Analysis |
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| Author:
| Wang, Sun-Chong
Petronis, Art |
| ISBN: | 978-1-4200-6728-6 |
| Publication Date: | Apr 2008 |
| Publisher: | CRC Press LLC
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| Imprint: | Chapman & Hall/CRC |
| Book Format: | Digital (delivered electronically) |
| List Price: | USD $59.95 |
Book Description:
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Illustrating results with examples based on real data, this book presents the statistical methods and tools to analyze DNA methylation microarray data. It describes wet-bench technologies that produce the data for analysis, explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections, and explores differential methylation and genomic tiling arrays. The authors show how cluster and network analyses can link the functions and roles of...
More DescriptionIllustrating results with examples based on real data, this book presents the statistical methods and tools to analyze DNA methylation microarray data. It describes wet-bench technologies that produce the data for analysis, explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections, and explores differential methylation and genomic tiling arrays. The authors show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. They also survey the open source software, public databases, and other online resources available for microarray research. An accompanying CD-ROM contains files of plots and many color images.