Design and Analysis of Cross-Over Trials |
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| Author:
| Jones, Byron
Kenward, Michael G. |
| ISBN: | 978-1-4398-6143-1 |
| Publication Date: | Oct 2014 |
| Publisher: | CRC Press LLC
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| Imprint: | Chapman & Hall/CRC |
| Book Format: | Digital (delivered electronically) |
| List Price: | USD $180.00USD $135.00USD $58.95 |
Book Description:
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This third edition contains new chapters on re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power. It employs the specially created R package Crossover, includes updates regarding period baselines and data analysis from very small trials, reflects the availability of new...
More DescriptionThis third edition contains new chapters on re-estimating sample size when testing for average bioequivalence, fitting a nonlinear dose response function, estimating a dose to take forward from phase two to phase three, establishing proof of concept, and recalculating the sample size using conditional power. It employs the specially created R package Crossover, includes updates regarding period baselines and data analysis from very small trials, reflects the availability of new procedures in SAS, and presents proc mcmc as an alternative to WinBUGS for Bayesian analysis.