Developmental Toxicology |
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| Author:
| Hansen, Deborah K.
Abbott, Barbara D. |
| Series title: | Target Organ Toxicology Ser. |
| ISBN: | 978-1-4200-5437-8 |
| Publication Date: | Oct 2008 |
| Publisher: | CRC Press LLC
|
| Book Format: | Hardback |
| List Price: | USD $190.00 |
Book Description:
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Highlighting latest advances in genetics and biochemistry, the completely revised Third Editionreviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicity data, highlighting...
More DescriptionHighlighting latest advances in genetics and biochemistry, the completely revised Third Editionreviews the field from basic science, clinical, epidemiological, and regulatory perspectives. Contributions from top opinion leaders in the field bring together developments in molecular embryology and cell biology as they apply to problems in developmental toxicology. It covers testing of pharmaceutical and environmental agents and interpretation of developmental toxicity data, highlighting mathematical and statistical techniques, as well as the effects of toxic exposure on the functional development of various organs.
The relationship between maternal and developmental toxicity is examined, and current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the regulatory aspects of testing and risk assessment. Pre- and post conceptional clinical care and genetic factors in clinical developmental toxicology are also discussed.
Key topics include: