Gene Targeting Protocols |
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| Editor:
| Kmiec, Eric B. |
| Series title: | Methods in Molecular Biology Ser. |
| ISBN: | 978-0-89603-360-3 |
| Publication Date: | Sep 1999 |
| Publisher: | Humana Press
|
| Imprint: | Humana |
| Book Format: | Hardback |
| List Price: | USD $169.99 |
Book Description:
|
This volume provides basic and advanced protocols for targeting at the genomic/chromosomal level. Recent advances in understanding the pathways of homologous recombination in eukaryotes have laid a foundation upon which new strategies can be built. Oligonucleotide-based, protein-based, and duplex DNA-based approaches are featured in this book. The protocols are aimed on improving gene selection and specificity, and are written in an convenient step-by-step fashion. Each protocol is...
More DescriptionThis volume provides basic and advanced protocols for targeting at the genomic/chromosomal level. Recent advances in understanding the pathways of homologous recombination in eukaryotes have laid a foundation upon which new strategies can be built. Oligonucleotide-based, protein-based, and duplex DNA-based approaches are featured in this book. The protocols are aimed on improving gene selection and specificity, and are written in an convenient step-by-step fashion. Each protocol is supported by a Notes section offering alternative ways of accomplishing the experiment and valuable troubleshooting advice.