Genome Analysis in R |
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Author:
| Michalak, Pawel |
Series title: | Chapman and Hall/CRC Mathematical and Computational Biology Ser. |
ISBN: | 978-1-4822-1037-8 |
Publication Date: | Apr 2020 |
Publisher: | CRC Press LLC
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Imprint: | Chapman & Hall/CRC |
Book Format: | Digital (delivered electronically) |
List Price: | USD $54.95 |
Book Description:
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In recent years the amount of biological sequence data available for research has increased significantly and complete genome sequences have become commonplace. Next-generation sequencing (NGS) is expected to revolutionize biomedical research. However, the analysis of millions of DNA/RNA sequences is becoming a real challenge as the capabilities of standard computers have been far exceeded. This book guides readers in the processing and analyzing of genome-wide data with minimum...
More Description
In recent years the amount of biological sequence data available for research has increased significantly and complete genome sequences have become commonplace. Next-generation sequencing (NGS) is expected to revolutionize biomedical research. However, the analysis of millions of DNA/RNA sequences is becoming a real challenge as the capabilities of standard computers have been far exceeded. This book guides readers in the processing and analyzing of genome-wide data with minimum computer RAM requirements. It focuses on practical solutions to a wide range of next-generation sequencing bioinformatic problems such as data import, read demultiplexing, trimming, quality checks, alignment, transformations, normalization, annotation, motif search, and differential expression. No prior programming knowledge is required.