Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models |
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| Author:
| Owen, Joel S.
Fiedler-Kelly, Jill |
| ISBN: | 978-1-118-78461-7 |
| Publication Date: | Jun 2014 |
| Publisher: | John Wiley & Sons, Incorporated
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| Book Format: | Digital download |
| List Price: | Contact Supplier contact
Contact Supplier contact
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Book Description:
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This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis. * Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects * Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model...
More DescriptionThis book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
* Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
* Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment
* Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
* Has datasets, programming code, and practice exercises with solutions, available on a supplementary website