Metal Sites in Proteins and Models Phosphatases, Lewis Acids and Vanadium |
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| Editor:
| Hill, H. A. |
| Volume Editor:
| Sadler, P. J.
Thomson, A. J. |
| Series title: | Springer Desktop Editions in Chemistry Ser. |
| ISBN: | 978-3-540-65553-4 |
| Publication Date: | Apr 1999 |
| Publisher: | Springer Berlin / Heidelberg
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| Imprint: | Springer |
| Book Format: | Paperback |
| List Price: | USD $54.99 |
Book Description:
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Biological chemistry is a major frontier of inorganic chemistry. Three special volumes devoted to
Metal Sites in Proteins and Models address the questions: how unusual ("entatic") are metal sites in metalloproteins and metalloenzymes compared to those in small coordination complexes? and if they are special, how do polypeptide chains and co-factors control this? The chapters deal with iron, with metal centres acting as Lewis acids, metals in phosphate enzymes, with...
More DescriptionBiological chemistry is a major frontier of inorganic chemistry. Three special volumes devoted to Metal Sites in Proteins and Models address the questions: how unusual ("entatic") are metal sites in metalloproteins and metalloenzymes compared to those in small coordination complexes? and if they are special, how do polypeptide chains and co-factors control this? The chapters deal with iron, with metal centres acting as Lewis acids, metals in phosphate enzymes, with vanadium, and with the wide variety of transition metal ions which act as redox centres. They illustrate in particular how the combined armoury of genetics and structure determination at the molecular level are providing unprecedented new tools for molecular engineering.