Multimodal Biomarkers for Central Nervous System Disorders Development, Validation, and Clinical Integration: Proceedings of a Workshop |
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| Author:
| National Academies of Sciences, Engineering, and Medicine,
Health and Medicine Division,
Board on Health Sciences Policy,
Forum on Neuroscience and Nervous System Disorders, |
| Editor:
| Norris, Sheena M. Posey
Childers, Eva
Carter, Sarah |
| ISBN: | 978-0-309-70848-7 |
| Publication Date: | Oct 2023 |
| Publisher: | National Academies Press
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| Book Format: | Ebook |
| List Price: | Contact Supplier contact
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Book Description:
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A key step towards reducing the burden of central nervous system (CNS) disorders is the identification of disease-specific biomarkers that can help predict, monitor, and guide treatment development. Recent technological advances have led to an increased number of biomarkers for different CNS disorders, providing the opportunity to generate multimodal biomarkers. While multimodal biomarkers can serve as promising tools to better diagnose and make accurate disease assessments, there...
More Description
A key step towards reducing the burden of central nervous system (CNS) disorders is the identification of disease-specific biomarkers that can help predict, monitor, and guide treatment development. Recent technological advances have led to an increased number of biomarkers for different CNS disorders, providing the opportunity to generate multimodal biomarkers. While multimodal biomarkers can serve as promising tools to better diagnose and make accurate disease assessments, there remain challenges in current data collection, standardization, and validation practices that impede in their development. Recognizing the need for increased CNS biomarker integration, the National Academies Forum on Neuroscience and Nervous System Disorders hosted a public workshop in March 2023 to explore steps toward this goal, including data collection for biomarker discovery, development, validation, and assessment of clinical utility. This Proceedings of a Workshop summarizes the discussions held during the workshop.