Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs

With more than 1500 full-scan mass spectra and quick-access data tables, this text provides a valuable reference for labs involved in the analysis of abused and therapeutic drugs. Part One illustrates approaches, mechanisms, and challenges pertaining to the use of isotopic analogs as internal standards for drug quantitation. A second section compiles mass spectra, including drugs and their analogs, as parent compounds and as derivatives resulting from various chemical derivatization...
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With more than 1500 full-scan mass spectra and quick-access data tables, this text provides a valuable reference for labs involved in the analysis of abused and therapeutic drugs. Part One illustrates approaches, mechanisms, and challenges pertaining to the use of isotopic analogs as internal standards for drug quantitation. A second section compiles mass spectra, including drugs and their analogs, as parent compounds and as derivatives resulting from various chemical derivatization approaches commonly encountered in today's labs. The third part provides corresponding tables of ion-pairs that can potentially be adapted to designate the drugs and their analogs in the analytical processes.