RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of MRNA Decay |
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Editor:
| Maquat, Lynne E. Kiledjian, Megerditch |
Series title: | Methods in Enzymology Ser. |
ISBN: | 978-0-12-374378-7 |
Publication Date: | Dec 2008 |
Publisher: | Elsevier Science & Technology
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Imprint: | Academic Press |
Book Format: | Hardback |
List Price: | USD $225.00 |
Book Description:
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Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a...
More DescriptionSpecific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation.