Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials |
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Author:
| Tango, Toshiro |
Series title: | Chapman and Hall/CRC Biostatistics Ser. |
ISBN: | 978-1-351-64814-1 |
Publication Date: | Sep 2017 |
Publisher: | CRC Press LLC
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Imprint: | Chapman & Hall/CRC |
Book Format: | Digital (delivered electronically) |
List Price: | USD $54.95 |
Book Description:
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This book provides the application of generalized linear mixed-effects models and its related models in the statistical design and analysis of repeated measures adopted in randomized controlled trials. With increasing concerns about intra-patient variability of treatment effects, the traditional ANCOVA-type methods can no longer cope with these variability and the need for sophisticated methods for estimating treatment effects by taking intra-patient variability into account is...
More Description
This book provides the application of generalized linear mixed-effects models and its related models in the statistical design and analysis of repeated measures adopted in randomized controlled trials. With increasing concerns about intra-patient variability of treatment effects, the traditional ANCOVA-type methods can no longer cope with these variability and the need for sophisticated methods for estimating treatment effects by taking intra-patient variability into account is immediate. The generalized linear mixedeffects model is one of such methods. The book emphasizes practical, rather than theoretical, aspects of mixed-effects models and interpretation of results.