Replicating Vaccines A New Generation |
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| Author:
| Dormitzer, Philip R. |
| Editor:
| Dormitzer, Philip R.
Mandl, Christian W.
Rappuoli, Rino |
| Series title: | Birkhäuser Advances in Infectious Diseases Ser. |
| ISBN: | 978-3-0346-0276-1 |
| Publication Date: | Nov 2010 |
| Publisher: | Springer Basel AG
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| Imprint: | Springer |
| Book Format: | Hardback |
| List Price: | USD $219.99 |
Book Description:
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Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up...
More DescriptionTechnological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.