Steroid Receptor Methods Protocols and Assays |
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| Editor:
| Lieberman, Benjamin A. |
| Series title: | Methods in Molecular Biology Ser. |
| ISBN: | 978-0-89603-754-0 |
| Publication Date: | Aug 2001 |
| Publisher: | Humana Press
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| Imprint: | Humana |
| Book Format: | Hardback |
| List Price: | USD $109.99 |
Book Description:
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Leading researchers present at readily reproducible laboratory techniques for the study of steroid receptor biology. Steroid hormone receptors represent a powerful system for the study of both the most fundamental molecular mechanisms of gene regulation and control, and the gross physiological responses of organisms to steroid hormones. The chapters cover the biochemical techniques including nuclear matrix receptor interaction, the yeast two-hybrid system, chromatin structure and heat...
More DescriptionLeading researchers present at readily reproducible laboratory techniques for the study of steroid receptor biology. Steroid hormone receptors represent a powerful system for the study of both the most fundamental molecular mechanisms of gene regulation and control, and the gross physiological responses of organisms to steroid hormones. The chapters cover the biochemical techniques including nuclear matrix receptor interaction, the yeast two-hybrid system, chromatin structure and heat shock proteins and receptors. Developmental protocols cover the differential gene expression and the antisense repression of hormone action. Protocols for drug discovery are also provided including an important chapter on orphan receptor ligands as well as chapters on bioinformatics, thus making this an essential manual for pharmacologists and biochemists working with steroid receptors.