The Biology of Germinal Centers in Lymphoid Tissue |
|
| Author:
| Thorbecke, G. Jeanette
Tsaigbe, Vincent K. |
| Series title: | Biotechnology Intelligence Unit Ser. |
| ISBN: | 978-3-540-64559-7 |
| Publication Date: | Nov 1998 |
| Publisher: | Springer
|
| Book Format: | Hardback |
| List Price: | USD $99.00 |
Book Description:
|
This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.
This book meets the demand of a recent surge of interest in germinal centers, the foci of antigen-induced, rapidly proliferating B lymphocytes, representing sites in mammalian lymphoid tissue where memory B cells are generated. Various aspects of the generation of germinal centers, the somatic hypermutation process and the cellular interactions involved in the selection process are discussed in detail. A chapter on germinal center-derived lymphomas completes the treatment.