The Human Complement System in Health and Disease |
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| Editor:
| Volanakis, John E. |
| ISBN: | 978-0-8247-9898-7 |
| Publication Date: | Feb 1998 |
| Publisher: | Taylor & Francis Group
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| Imprint: | CRC Press |
| Book Format: | Hardback |
| List Price: | USD $120.00USD $209.95USD $315.00 |
Book Description:
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This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease
This authoritative, single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases.
Written by over 40 international experts from North America, Europe, and Asia, The Human Complement System in Health and Disease
- describes the molecular architecture of the complement system
- details the structure of complement genes
- discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins
- analyzes complement organization and activation, including phylogeny and the newly discovered lectin pathway
- elucidates the regulation of complement gene expression and the structure and function of bioactive peptides
- explicates opsonic and immunoregulatory properties of complement fragments, endothelial responses, and interactions with viruses and bacteria
- and more!